Phenotypic and genomic analysis of an exceptional case of enteropathy associated T-cell lymphoma
Approximately half (30–50%) of all extra-nodal non-Hodgkin lymphomas arise from the gastrointestinal tract with more frequent localisation in the stomach compared to other intestinal sites . Among them, the fast majority originate from B-cells whereas peripheral T-cell lymphomas (PTCL), although frequently manifested in the skin and upper airway, seldomly develop in the gastrointestinal tract at initial presentation. Those PTCL that do primarily affect the digestive tract are most commonly located in the small intestine . PTCL associated with coeliac disease (CD) are classified as (type I) enteropathy associated T-cell lymphoma (EATL) according to the current WHO classification . With an annual incidence rate of 0.5–1 per million people in the Western countries this type of EATL accoun...MedWorm Message: Register for MedMatcha, MedWorm's medical advertising network, and receive $5 free advertising.
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