Non-axial bone fracture but not depression as a risk factor for coeliac disease
This study examined the hypothesis that patients taking antidepressants or presenting with fractures could represent new subgroups at higher risk for coeliac disease. A total of 105 and 199 consecutive patients presenting to hospital taking antidepressants and/or with a fracture was screened with IgA tissue transglutaminase and had their IgA serum levels quantified. Patients with positive serology were offered further diagnostic and management follow up. No patients taking antidepressants had positive serology. Seven with fractures had elevated titres of IgA tissue transglutaminase. All of these patients had presented with non-axial fractures, representing a prevalence of 5.2% (95% confidence interval: 1.4[ndash]8.9%). Uptake of further investigation and management was poor. Patients prese...MedWorm Sponsor Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.
http://www.medworm.com/index.php?rid=3365486&cid=c_1_49_f&fid=28862&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1445-5994.2009.02153.x
