[Celiac News] Ongoing remission after intensive All-type chemotherapy in pediatric intestinal T-cell lymphoma

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Ongoing remission after intensive All-type chemotherapy in pediatric intestinal T-cell lymphoma
           

A rare case of primary intestinal T-cell lymphoma (ITL) of an 8-year-old boy is reported. Medium- to large-sized tumor cells were [beta]F1+, CD3+, CD8+. TIA-1+, but CD4-, CD5-, CD30-, CD56-, CD20-, CD79a-, TdT-, consistent with an intraepithelial lymphocyte (IEL) origin. They showed monoclonal rearrangement of the T-cell receptor [gamma]-chain and no evidence of EBV infection. No clinical, histologic, laboratory, or genetic evidence of celiac disease was detected. In adults, ITL is often associated with enteropathy and has a very poor outcome. Our patient remains in first remission 30 months after finishing the acute lymphoblastic leukemia protocol COALL-07-03 high risk standard. Pediatr Blood Cancer © 2009 Wiley-Liss, Inc. (Source: Pediatric Blood and Cancer)MedWorm Sponsor Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.
           

http://www.medworm.com/index.php?rid=3139806&cid=c_1_6_f&fid=33611&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpbc.22330